Cross-References

Important

This section is a fundamental building block of any SOP

The ‘Cross-References’ section of an SOP should list other controlled documents that support or relate to the procedure. Cross-references ensure that users can easily identify associated SOPs, validation documents, and equipment instructions necessary for performing the procedure correctly.

Depending on the procedure, cross-references may include:

  • Associated SOPs: Related procedures that describe upstream or downstream processes, such as wet-lab procedures or reporting workflows.

  • Validation and verification documents: References to documents establishing the analytical performance, accuracy, and reproducibility of the pipeline or procedure.

  • Equipment or instrument SOPs: Instructions for using specific laboratory instruments or software platforms required for the procedure.

  • Guidelines and standards: Relevant internal or external guidelines, such as laboratory standards, regulatory requirements, or best practice documents.

Attention

If the organisation does not have an electronic document management system (eQMS), cross-references should include version numbers and revision dates to ensure users access the correct version.


Example content:

🧬 Bioinformatics QC Procedure

Example content from a bioinformatics SOP outlining the procedure for assessing the quality of Illumina sequencing data prior to downstream bioinformatics analyses.


Cross-references

The following documents support or are directly related to this procedure:

Document Index

Document Title

SOP045

Using the NextSeq 550

SOP064

A guide to bioinformatics in pathogen genomics

SOP065

Operational testing of bioinformatics pipelines

Bioinformatics routine tasks

Validation of the bioinformatics QC pipeline

👩‍🔬 Staff Training Procedure

Example content from an SOP outlining a training procedure


Cross-references

This SOP should be read alongside:

  • IIB_QMS_001: Competency Assessment SOP

  • IIB_QMS_003: Training Matrix and Staff Competency Framework

  • IIB_QMS_004: Record Keeping and Documentation SOP

  • Topic-specific training SOPs (e.g., Galaxy Workflow Development Training SOP)

🌌 Galaxy Training Procedure

Example content from a training SOP detailing the standardised procedure for training on the Galaxy platform


Cross-references

This SOP should be read alongside:

🧪 Laboratory Procedure

Example content from a wet-lab SOP outlining the procedure for preparing sequencing libraries using the Illumina DNA Prep kit.


Cross-references

The following documents support or are directly related to this procedure:

Document Index

Document Title

SOP 023

Acceptance testing

SOP 011

Thermocycler operation and maintenance

SOP 012

Pipette use, maintenance and calibration

SOP 013

Centrifuge operation and maintenance

SOP 084F2

UDI indexing log

SOP 084F1

Illumina DNA prep worksheet

DOC 011

Illumina DNA prep library preperation kit: Instructions for use

VA 021

Validation of Illumina DNA Prep library preperation kit for Next Generation Sequencing

💻 Code Update & Review Procedure

Example content from an SOP outlining the procedure for updating and reviewing code within the Luma Genomics Unit (LGU).


Cross-references

The following documents support or are directly related to this procedure:

  • DOC-ADVISOEXAMPLE-001: LGU standards guidelines for Python

  • DOC-ADVISOEXAMPLE-002: LGU standards guidelines for Nextflow

✅ Validation Procedure